Arms and the Men

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The Value of ARMS/PCR and RFLP/PCR In Prenatal Diagnostic Accuracy Of -Thalassemia

Background: It is estimated that about 3,000 pregnancies in Iran are at risk for b-thalassemia each year. Objective: To evaluate the diagnostic accuracy of combination of ARMS/PCR and  RFLP/PCR techniques in prenatal diagnosis of b-thalassemia.Methods: Sixty-seven b-thalassemia carrier families were enrolled in this study. To analyze b-globin gene, amplification refractory mutation system (ARMS...

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ژورنال

عنوان ژورنال: Science

سال: 1987

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.238.4823.9